A new approach for the segregation of monaural sound mixtures is presented based on the principle of temporal coherence and using auditory cortical representations.Temporal coherence is the notion that perceived sources emit coherently modulated features that evoke highly-coincident neural response patterns.By clustering the feature channels with c
In many plant species, conflicts between divergent elements of the immune system, especially nucleotide-binding oligomerization domain-like receptors (NLR), can lead to hybrid necrosis.Here, we report deleterious allele-specific interactions between an NLR and a non-NLR gene cluster, resulting in not one, but multiple hybrid necrosis cases in Arabi
Lorlatinib is a third-generation ALK inhibitor that can overcome the largest number of acquired ALK resistance mutations, including the solvent-front mutation G1202R.Here, we report, for the first time, Feet a novel, sequentially-evolved EML4-ALK variant 3 G1202R/S1206Y double mutation in cis detected in a patient with ALK-positive NSCLC after dise